BEAM Alliance shares news of data of ILP100 killing multi drug resistant bacteria
Link to open source publication in Infectious Diseases and Therapy: https://link.springer.com/article/10.1007/s40121-025-01137-y
Link to open source publication in Infectious Diseases and Therapy: https://link.springer.com/article/10.1007/s40121-025-01137-y
The topic of the Fellowship centers on exploring the ongoing initiatives in Multi-Drug Resistant (MDR) pathogen testing, treatment and policy reform with the aim to participate to the #solution identifying and collaborating with stakeholders and discover how the companys resent research in fighting MDR microbes with therapeutic microbes in different diseases may best deliver impact to patients.
"The implications of this study are substantial, extending beyond immediate therapeutic benefits to broader impacts on the field of colitis treatment and potentially other inflammatory diseases. The methodology used in this study could be adapted for other inflammatory diseases by engineering L. reuteri to express different therapeutic proteins. This broadens the potential applications of this approach beyond colitis" Our asset ILP100-Oral is currently at IND stage in development with: ✅ FDA pre-IND meeting completed allowing first-line-treatment ✅ SITU-GUT clinical phase 1/2a trial developed with KOLs for ICI-induced colitis stage 1 and 2 ✅CMC and GMP synergies with ILP100-Topical already in Phase 2 clinical developments with IND cleared for pivotal study ✅ Exceptional COGs, stability in room temperature ✅ Projections of blockbuster potential ➡️ The company seeking a suitable partner to accelerate the clinical development for this asset and share the expected joys of developing ground breaking research 💊 and the expected value generated💰 💰
American Journal of Physiology-Gastrointestinal and Liver Physiology, June 2024 issue Title: Oral administration of CXCL12-expressing Limosilactobacillus reuteri improves colitis by local immunomodulatory actions in preclinical models Authors: Emelie Öhnstedt, Cristian Doñas, Kristel Parv, Yanhong Pang, Hava Lofton Tomenius, Macarena Carrasco López, Venkata Ram Gannavarapu, Jacueline Choi, Maria Ovezik, Peter Frank, Margareth Jorvid, Stefan Roos, Evelina Vågesjö, and Mia Phillipson
Special thanks to the author PhD student Vilhelmiina Haavisto, ETH Zurich, for the very well written piece and the interesting folklore history of Angels Glowing, nature is fantastic, especially when bioluminescent and when engineering is possible to utilise the already existing properties in new ways for the benefit of people.